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Adenoid cystic carcinoma, a tumor type that represents less than 1 percent of all breast carcinomas, generally is treated with surgery alone, either lumpectomy or mastectomy. Steven Chen, assistant professor of surgical oncology, wanted to find out if adding radiation therapy to surgery would improve outcomes for patients.

Chen’s research was sparked by a patient whom he cared for two years ago. “I had seen a patient with this type of cancer, and wasn’t sure what to do with her after surgery,” Chen said. “I wondered if she was supposed to get radiation therapy.”

Chen took the case to a meeting of other cancer specialists. All agreed that there was no solid evidence available about the value of radiation therapy for this type of tumor. Physicians do not like to give patients any radiation dose when it is not clear that it could be effective.

Published online this month in the Journal of Surgical Oncology, Chen’s study identified 376 patients across the country diagnosed with adenoid cystic carcinoma of the breast in the Surveillance, Epidemiology, and End Results (SEER) registry maintained by the National Cancer Institute. All of the patients had undergone breast cancer surgery between 1988 and 2005. Among them, 129 (34 percent) also had received radiation therapy.

“We found that the women who got radiation treatment did better,” Chen said. “Even after accounting for age, tumor stage and type of surgery, radiation therapy still cut the death rate by 56 percent overall.”

Among women who had radiation therapy after lumpectomy, survival rates after five years for those undergoing surgery and radiation were 94 percent; survival rates were 82 percent for those having surgery alone. By 10 years, that gap had widened: 86 percent of those undergoing radiation were still alive, whereas only 67 percent of those having surgery alone were still alive.

Because of the relatively small number of patients in the study, results were limited to women with early-stage disease. And because so few of the women in the study had a mastectomy, the sample was too small to determine a benefit from radiation therapy for those patients.

Chen hopes the research gives cancer specialists helpful information in choosing therapeutic approaches for patients with this type of breast cancer.

“We hope surgical oncologists will see this study and start referring patients to radiation oncology more often,” he said. “There are good reasons why a woman might choose not to have radiation therapy, but they won’t have an opportunity to have that discussion if they don’t get a referral.” by Dorsey Griffith, PhysOrg

The popular Outlander LS, in both 2WD and 4WD, was selected for Large Wagon and Large SUV categories respectively, while Triton GL and GLX were both selected for the 2WD and 4WD Utility categories.

Mitsubishi Motors NZ national fleet sales manager Mike Davidson is delighted with the decision.

“The endorsement is a reflection of the quality and value of both models, our industry-leading 10/5 Diamond Advantage Warranty and the strength of the Mitsubishi network,” he said

“Ever since its launch in 2005, Outlander has been a New Zealand favourite and it continues to top the sales charts in its class. Triton has moved from strength to strength and is recognised for its class-leading 4WD and safety features. It is the only option in the diesel ute segment with active stability control and the GL configuration is the only 4WD ute with rear diff lock as standard.

“The all-of-government procurement process reviewed 518 vehicles provided by 14 suppliers. Up to eighty five percent of the vehicles available to agencies could potentially be supplied by Mitsubishi and two other suppliers,” said Mr Davidson.

Vehicles were assessed across a range of criteria – including total cost of ownership, safety, fit for purpose, service network and warranty and environmental impacts – which, for the latter, followed an approach to fuel consumption and emissions consistent with the United Nations Environment Programme guidelines.

Minister for Economic Development Gerry Brownlee expects that over five years, the deal will save taxpayers $18.5 million or 8% of the Government’s current vehicle expenditure at the same time as improving safety and environmental standards. Scoop

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The research has indicated that fat is genetically different in men and women.

“Given the difference in gene expression profiles, a female fat tissue won’t behave anything like a male fat tissue and vice versa,” said Deborah Clegg, of the UT Southwestern Medical Center.

“The notion that fat cells between males and females are alike is inconsistent with our findings,” he said.

Mice store their fat similar to humans in a sexually dimorphic pattern. Just like human males, male mice store their fat in the belly and midsection area while females store fat in their hips, thighs and buttocks.

“We found that out of about 40,000 mouse genes, only 138 are commonly found in both male and female fat cells,” said Clegg.

“This was completely unexpected. We expected the exact opposite – that 138 would be different and the rest would be the same between the sexes.”

“The research being performed by Dr. Clegg and colleagues underscores the importance of understanding the differences in fat deposition in men and women,” said Viviana Simon of Society for Women’s Health Research

“The ability to manipulate how and where in the body fat is deposited holds the promise of helping researchers develop strategies to prevent or delay the development of chronic conditions such as diabetes and cardiovascular disease,” added Simon.

The findings appeared in the International Journal of Obesity. Newstrack India

People grow old only by deserting their ideals. Years may wrinkle the skin, but to give up interest wrinkles the soul. Worry, doubt, self-distrust, fear and despair – these are the long, long years that bow the head and turn the growing spirit back to dust. Thus, before the sunsets for everyone, man and woman tend to become themselves one under a lifelong commitment of marriage. And considering the use of military coins during the ceremony would be an added niche and a unique idea. And towards it also, having a custom coins prepared for distribution to the guests and visitors are a great way to have a keepsake about that special day on their lives.

According to an insider, Britney, 28, was half-joking about creating “a huge, over-the-top Hollywood affair” at first. But when the two couples went back to her Calabasas, Calif., home, the sisters couldn’t stop talking about it.

Britney and Jamie Lynn Spears: The famous sisters have hatched a plan to hold the wedding of the century! Finally settled and happy (with boyfriends Jason Trawick and Casey Aldridge respectively) Britney and Jamie Lynn recently discussed the potential details for an unforgettable double wedding! OK! have the details on what the dream guest list might be, why the girls are ready now and what the ceremony could look like. OK! Magazine

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Experts blame an erratic diet as a predominant cause of stress, which usually spans into snack breaks, tea breaks and more snack breaks. Though we can do better by tweaking our diet chart to include foods that curb stress.

Here is a list of eight foods that’ll do the trick …

Yoghurt : Yoghurt works well especially in summer, as it is light and digests easily. Says Dr Shikha Sharma, doctor and wellness expert, “Yoghurt or any dairy product is rich in tyrosine which increases the serotonin level in the brain.” She simplifies this for us, “Proteins increase neurohormone in the brain which eases stressed nerves and calms you down.” If plain yoghurt bores you, try the ready-to-scoop-up, fruit flavoured version. Strawberry, blackcurrant, litchi and mango are some popular flavoured yoghurt.

Dark chocolate : Dark chocolates are nothing short of a delicacy, they send our taste buds spiralling. But there is more to dark chocolate such as lowering stress hormone levels and improving other stress-related bio-chemical imbalances. Agrees Chef Sachin Sahgal, food and nutrition expert, Tivoli Garden Hotel, “Our body requires a fair dose of antioxidants, and in chocolate the antioxidants come in the form of flavonoids. Besides, the flavonoids are maximum in dark chocolate.” Chocolates also go a long way in enhancing mood. Explains Chef Sahgal, “Chocolates are good aphrodisiacs, also known as ‘love chemical’ which is a mood stimulant and booster. They contain phenethylamine – a safe natural ingredient that is released in the brain when positive emotions such as falling in love are experienced.”

Citrus fruits : Any fruit of your choice is good enough. “Fruits have natural sugar which de-stresses the mind. It is best to go for citrus fruits or any summer fruit. Besides, the natural sugar in fruits is very healthy for the body. Make any one meal fruit rich, and you will feel the difference in your energy levels,” says Dr. Shikha Sharma.

Almonds : Almonds not only promote shiny mane, but also work as stress relievers. Elaborates Chef Sahgal, “Almonds are packed with vitamin B2, vitamin E, magnesium, and zinc. B vitamins and magnesium are involved in the production of serotonin, which helps regulate mood and relieve stress. Zinc fights some of the negative effects of stress, while vitamin E is an antioxidant that destroys the free radicals related to stress and heart disease.”

Herbal tea : Black tea or herbal tea checks calories, and at the same time betters your mood. Justifies Dr. Shikha Sharma, “Chamomile tea, jasmine tea, tulsi tea and other herbal variants of tea do wonders to our system. The herbs act like medicine in calming and relaxing our mind.”

Fish : An abundant source of Omega 3 fatty acids, fish contains important B vitamins, particularly the renowned stress fighters B6 and B12. “In fact, B12 is one of the most important vitamins involved in the synthesis of the ‘happy’ brain chemical serotonin; a vitamin B12 deficiency can even lead to depression. Seafood contains high amount of zinc which relives one from stress,” reasons Chef Sahgal.

Broccoli : Broccoli is such a happy, green vegetable. It works magic when added to pasta, rice, salad or simply sautéed with mushrooms and baby potatoes. But did you know the vegetable had stress-busting properties? “Broccoli is chock-full of stress-relieving B vitamins including folic acid, which is also part of the B vitamin family. Folic acid helps relieve stress, anxiety, panic, and even depression. It is also high in fiber content which is helpful in treating constipation and the loose stools associated irritable bowel syndrome which is one of the long term effects of stress,” says he.

Garlic : Outside of keeping vampires at bay, garlic eases tension and stress, and reduces glucose levels in the body. If you are not sure about how else to include garlic in your diet, pickle it. Garlic pickle lives long and tastes good with quick snacks, rice and chapati. Shares Chef Sahgal, “The development of hypertension is implicated by a state called as oxidative stress where our body produces reactive oxygen species much higher than its antioxidant capacity. Garlic is rich in antioxidants and helps restore these antioxidants which in turn soothe our stress levels.” By Anwesha Mittra, The Times of India

Well, the grim statistics should wake us all up. Towards it, something concrete steps should have been done to possibly consider institutionalizing intervention measures in the workplace. Hence, thwart any attempt of your family members into taking some of the illegal drugs and substance. Though addiction treatment is now readily available, better yet, advice them to stop drug addiction or else, they will be losing their life. We only live once, and why make ourselves become under the mercy and the influence of those drugs which only bring chaos, turmoil and instability to your life?

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